From 1987 to 1996, forty-two isolates of Salmonella paratyphi A were collected from Taiwan, China and other Southeast Asian countries. Pulsed-field gel electrophoresis (PFGE) was used to differentiate the genomic DNA of these isolates with four different restriction enzymes, Xba I, Not I, Spe I and Avr II. Based on the PFGE profiles obtained, Avr II allowed the most discriminatory results among these restriction endonucleases. By Avr II digestions, 42 isolates of S. paratyphi A were differentiated into three clones. The predominant clone accounted for 85.7% of the tested strains (36 in 42 isolates) and was found in many countries of Southeast Asia. Thus, S. paratyphi A appears to have limited genetic diversity in evolutionary process.
Pan, T.-M.; Lin, C.-S.; Wang, T.-K.; Tsai, J.-L.; Ho, S.-I.; and Lee, C.-L.
"Molecular subtyping of Salmonella enterica serovar paratyphi A from Southeast Asia,"
Journal of Food and Drug Analysis: Vol. 6
, Article 9.
Available at: https://doi.org/10.38212/2224-6614.2903