Simultaneous determination of 24 congeners of 2- and 3‑monochloropropanediol esters and 7 congeners of glycidyl esters using direct multi-residue analytical LC-MS/MS methods in various food matrices

Ching-Chang Lee, Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan
Bo-Lun Lin, Department of Food Safety/Hygiene and Risk Management, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan
Yi-Wen Huang, Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan
Ning-Syuan Hsu, Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan
Wei-Hsiang Chang, Research Centre of Environmental Trace Toxic Substances, College of Medicine, National Cheng Kung University, Tainan 704, TaiwanFollow

Abstract

Glycidyl esters (GEs) and 2- and 3-monochloropropanediol esters (MCPDEs) are emerging process-generated food contaminants known as possible carcinogens. Herein, a direct method is developed and validated for the first time to simultaneously quantify seven GEs and twenty-four MCPDE congeners of processed foods using liquid chromatography-tandem mass spectrometry in a single sequence without ester cleavage or derivatisation, thereby allowing for the simultaneous analysis of numerous food matrices with high accuracy and precision. Our results show levels of GEs varying from

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Recommended Citation

Lee, Ching-Chang; Lin, Bo-Lun; Huang, Yi-Wen; Hsu, Ning-Syuan; and Chang, Wei-Hsiang (2023) "Simultaneous determination of 24 congeners of 2- and 3‑monochloropropanediol esters and 7 congeners of glycidyl esters using direct multi-residue analytical LC-MS/MS methods in various food matrices," Journal of Food and Drug Analysis: Vol. 31 : Iss. 1 , Article 4.
Available at: https://doi.org/10.38212/2224-6614.3442