Chemiluminescence of lucigenin-tetracycline and itsapplication for sensitive determination of procyanidin

Authors

Shuai Quan, College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, 541004, China
Kaixiang Ji, College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, 541004, China
Fangshuo Liu, State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, PR China
Tesfaye Hailemariam Barkae, State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, PR China
Mohamed Ibrahim Halawa, Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt
Saima Hanif, Department of Biological Sciences, National University of Medical Sciences (NUMS), The Mall, Abid Majeed Road Rawalpindi, Punjab, 46000, Pakistan
Baohua Lou, State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, PR ChinaFollow
Jianping Li, College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, 541004, ChinaFollow
Guobao Xu, College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, 541004, ChinaFollow

Abstract

Tetracycline was reported to trigger intense lucigenin chemiluminescence (CL). Based on its significant quenching to lucigenin-tetracycline CL, procyanidin was detected. The mechanism of the lucigenin-tetracycline CL and its quenching by procyanidin were proposed. Under the optimum conditions, the calibration curve is linear in the range of 10-1000 nM for procyanidin with a detection limit of 4.4 nM. The RSD for nine replicate determinations of procyanidin was less than 1.7%. Moreover, this method was satisfactorily applied to the determination of procyanidin in human urine samples and health food capsule of grape seed.

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Recommended Citation

Quan, Shuai; Ji, Kaixiang; Liu, Fangshuo; Barkae, Tesfaye Hailemariam; Halawa, Mohamed Ibrahim; Hanif, Saima; Lou, Baohua; Li, Jianping; and Xu, Guobao (2022) "Chemiluminescence of lucigenin-tetracycline and itsapplication for sensitive determination of procyanidin," Journal of Food and Drug Analysis: Vol. 30 : Iss. 2 , Article 9.
Available at: https://doi.org/10.38212/2224-6614.3411

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