Metabolic profiling investigation of Fritillaria thunbergii Miq. by gas chromatography–mass spectrometry

Authors

M.-C. Cui
S.-J. Chen
H.-H. Wang
Z.-H. Li
H.-J. Chen
Y. Chen
H.-B. Zhou
X. Li
J.-W. Chen

Abstract

Thunberg fritillary bulb (the dry bulbs of Fritillaria thunbergii Miq.), a traditional Chinese Medicine, is widely applied as an expectorant and antitussive. In this investigation, the primary metabolites of bulbs, flowers, leaves, and stems of F. thunbergii were analyzed by gas chromatography–mass spectrometry. Principal component analysis, partial least squares-discriminate analysis, orthogonal projection to latent structures-discriminate analysis, and heat map analysis showed that there were dissimilar metabolites, and a negative correlation between amino acids and saccharides in different analytes. Furthermore, carbodiimide, tryptophan, glucose-6-phosphate, xylose, 2-piperidinecarboxylic acid, monoamidomalonic acid, phenylalanine, and histidine were found to play an important role in the plant metabolism net of F. thunbergii. © 2017

Abstract Image

ScienceDirect Link

10.1016/j.jfda.2016.10.003

Recommended Citation

Cui, M.-C.; Chen, S.-J.; Wang, H.-H.; Li, Z.-H.; Chen, H.-J.; Chen, Y.; Zhou, H.-B.; Li, X.; and Chen, J.-W. (2018) "Metabolic profiling investigation of Fritillaria thunbergii Miq. by gas chromatography–mass spectrometry," Journal of Food and Drug Analysis: Vol. 26 : Iss. 1 , Article 21.
Available at: https://doi.org/10.1016/j.jfda.2016.10.003

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https://www.sciencedirect.com/science/article/pii/S1021949816301521/pdfft?md5=3b8f9cedb168f1bac4b6f0b6ab83be0e&pid=1-s2.0-S1021949816301521-main.pdf