Water-soluble phenolic compounds and their anti-HIV-1 activities from the leaves of Cyclocarya paliurus
Eight phenolic compounds including five glucuronides were isolated from the leaves of Cyclocarya paliurus (Batal.) Ijinskaja, which is used as a source of tea. Their structures were characterized by spectroscopic methods. The results of biological assay showed that compounds 1 and 5 had good activities against HIV-1 induced cytopathic effects in C8166 lymphocyte at non-cytotoxic concentrations, with EC50 values of 31.74 and 10.76 μM, and therapeutic index (TI) values of >13.02 and 25.46, respectively. Relationship between molecular structures and their bioactivities was discussed.
Zhang, J.; Huang, N.; Lu, J.-C.; Li, X.; Wang, Y.-H.; Yang, L.-M.; Zheng, Y.-T.; and Xiao, K.
"Water-soluble phenolic compounds and their anti-HIV-1 activities from the leaves of Cyclocarya paliurus,"
Journal of Food and Drug Analysis: Vol. 18
, Article 2.
Available at: https://doi.org/10.38212/2224-6614.2230